Membranes Archive - BioMembrOS

Article in Membranes Journal

We are proud to share that we published a new paper – „A Validated CFD Model for Gas Exchange in Hollow Fiber Membrane Oxygenators: Incorporating the Bohr and Haldane Effects“ – in the open-access journal Membranes. The study, led by Seyyed Hossein Monsefi Estakhrposhti as first author, presents a new computational model to better understand how oxygen and carbon dioxide are exchanged in hollow-fibre membrane oxygenators — devices that play a vital role in supporting patients with severe respiratory failure.

By incorporating important physiological effects that are often overlooked in existing models, the team was able to create a much more realistic picture of how gas exchange happens under clinical conditions. Their work was carefully validated with experimental data and showed very high accuracy. This approach offers new opportunities for designing and testing future oxygenators more efficiently, with less reliance on costly and time-consuming laboratory trials.

This publication highlights the innovative research carried out within BioMembrOS, and also underlines how collaboration across engineering and biomedical sciences can help drive forward the next generation of artificial respiration technologies.

The full article is available open access in Membranes: https://www.mdpi.com/2077-0375/15/9/268

Jing Jing Xu published Article in Polymers Journal

We are thrilled to congratulate our PhD Researcher, Jing Jing Xu from TU Wien, on the publication of her latest research article, „From Soft Lithography to 3D Printing: Current Status and Future of Microfluidic Device Fabrication“ in the well-regarded Polymers journal. This achievement highlights the comprehensive analysis conducted by Jing Jing Xu, where she systematically compared different fabrication methods, assessed their practical applications, and examined key factors such as efficiency, precision, and biocompatibility to provide a well-rounded perspective on the current and future landscape of microfluidic device fabrication.

Microfluidic devices play a crucial role in various scientific and industrial applications, including biomedical diagnostics, drug delivery, and chemical analysis. In her article, Jing Jing Xu explores the transformative potential of 3D printing as an alternative to traditional soft lithography techniques. The study provides an in-depth review of various 3D printing methods, particularly photopolymerization techniques, fused deposition modeling, and material jetting, and evaluates their advantages in terms of cost efficiency, geometric complexity, and material versatility.

The article also addresses key challenges limiting the widespread adoption of 3D printing for microfluidic applications, including material transparency and biocompatibility. Recent advancements in printing technologies and new material developments are highlighted, demonstrating progress in overcoming these barriers. Additionally, the study discusses future trends such as improvements in printing resolution and speed, the emergence of bioprinting for organ-on-a-chip applications, sustainability considerations, and the impact of regulatory frameworks on the field.

Published in Polymers, a peer-reviewed journal known for its focus on polymer science and engineering, this research provides valuable insights into the evolving landscape of microfluidic device fabrication. By bridging the gap between traditional and emerging fabrication techniques, this review offers researchers and engineers a clearer understanding of the strengths and limitations of each approach, aiding in the selection of the most suitable methods for specific applications.

We extend our heartfelt congratulations to Jing Jing Xu for this valuable contribution and look forward to seeing her continued impact in the field of polymer science and microfluidics.

For more details, you can access the full article in Polymers: https://www.mdpi.com/2073-4360/17/4/455.

BioMembrOS Kick-Off Meeting

The Kick-Off meeting of the BioMembrOS Pathfinder Open project took place at TU Wien this week.

Thanks to all partners for the inspiring presentations and stimulating discussions and thanks to our Vice Rector for Research Peter Ertl for joining us!

BioMembrOS is an EIC Pathfinder Project aiming to develop a new generation of radically new membrane structures for artificial respiration by mimicking the best – respiration in birds and fish, and is coordinated by the interfaculty TU Wien Biofluidslab.